Nursing care in the patient with high-grade glioma treated by 5-ala (Gliolan®) induced fluorescence-guided surgery.
Abstract
Introduction. High-grade glioma surgery, associated with chemo / radiotherapy, improves the patient's quality of life. However, the surgical goal is to resect as much tumor as possible, avoiding damaging neighboring healthy brain tissue. This is possible thanks to the guided surgery with fluorescence induced with 5-aminolevulinic acid. The aim of this study has been to review the evidence on nursing care to the patient who underwent surgery using this technique.
Methodology. A systematic review protocol based on the PRISMA declaration was designed. The CASPe guidelines allowed to evaluate the methodological quality of the evidence located in Cuiden, Scielo, Pubmed, WOS, Science Direct, Virtual Health Library, Ciber Index, Scopus, Up to Date, Clinical Key and Google Scholar. A seniority of less than 5 years, moderate / high quality, English, French, Portuguese or Spanish were the main selection criteria.
ResultsNo evidence could be located about nursing care in the study area. We opted for a narrative review, based on the available evidence, on relevant aspects of care for these patients. The successful administration of 5-aminolevulinic acid conditions the success of the surgery. It will be avoided to expose the patient to light sources in the 24h after the administration of the drug; fundamental to prevent adverse reactions. Radical resection vs. Partial adjuvant with radio / chemotherapy should be weighted to offer maximum survival and quality of life to the patient.
Conclusions. Nursing care in patients treated with fluorescence-guided surgery includes the importance of patient light protection, knowledge of the drug and its adverse effects, and informing patients, families, and professionals about the procedure. Care research in this field should be strengthened.
